In China, the infertility rate among couples of childbearing age continues to rise, and difficulty conceiving naturally has become a common challenge for countless families. Quality IVF medical resources in China are in short supply, so many couples trying to conceive have begun to consider overseas assisted reproduction. In this context, Georgia, with its mature IVF technology, has attracted a lot of attention. So who is third-generation IVF in Georgia suitable for? Gebe is here to walk you through it.
1. One or both partners have chromosomal abnormalities
This includes structural abnormalities such as balanced translocation, Robertsonian translocation, and inversion, or a previous pregnancy with a chromosomal abnormality. In these cases, the probability of embryonic chromosomal imbalance is significantly higher. PGT-SR (preimplantation genetic testing for structural rearrangements) can identify and screen out abnormal embryos before transfer. Qualified laboratories in Georgia are equipped with NGS high-throughput sequencing equipment and can cover whole-chromosome screening.
2. There is a clear risk of a monogenic genetic disease
Both partners are carriers of the same monogenic genetic disease (such as thalassemia, spinal muscular atrophy, cystic fibrosis, etc.), or one partner is affected. PGT-M can test for known pathogenic sites and select embryos that do not carry the pathogenic gene for transfer.
3. Couples trying to conceive at an advanced maternal age
When the woman is 35 or older, the probability of egg chromosomal abnormalities increases with age, and the risk of embryo arrest and miscarriage rises. Some reproductive centers in Georgia recommend PGS screening for women aged 39 and above, or for older women with a specific history of failure. The role of third-generation IVF is to screen out embryos with chromosomal abnormalities, not to reverse egg quality.
4. Recurrent pregnancy failure
This includes two or more consecutive unexplained natural miscarriages, or three or more transfers of high-quality embryos that still failed to implant. If examinations such as hysteroscopy have ruled out clear uterine structural problems, PGT screening can help determine whether the failure is related to embryonic chromosomal abnormalities.
5. Severe abnormalities in the male partner's reproductive indicators
Severe oligospermia or asthenozoospermia, teratozoospermia, or elevated sperm DNA fragmentation rate (DFI), with poor embryo development after conventional fertilization. In such cases, after fertilization is achieved with ICSI, blastocyst PGT screening can be performed at the same time to improve transfer stability. However, it should be noted that PGT does not improve sperm DNA integrity itself, and for elevated DFI, targeted conditioning is still recommended first.
6. People with limited domestic indications or who cannot proceed under domestic policy
Third-generation IVF in China requires strict medical indications and an approval process. Qualified institutions in Georgia offer PGT-A chromosome screening to eligible families, and the process is relatively direct. In addition, the revised Reproductive Health Law of 2026 includes single individuals and same-sex couples within the legal scope of assisted reproduction.
Who is third-generation IVF in Georgia suitable for? Through the introduction above, everyone should have a better understanding. If you fall into one of these situations, you can consider IVF in Georgia. If you are unsure how to evaluate overseas IVF options, you can call us for a consultation. We will provide detailed information to help you learn more about overseas IVF.